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higg  (Sino Biological)


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    Structured Review

    Sino Biological higg
    Higg, supplied by Sino Biological, used in various techniques. Bioz Stars score: 94/100, based on 22 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/higg/Human+IgG4%2C+kappa+Isotype+Control/pm41611695-278-10-12
    Average 94 stars, based on 22 article reviews
    higg - by Bioz Stars, 2026-10
    94/100 stars

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    Related Articles

    other:

    Article Title: Anti-TLR2 immunotherapy modulates neuron-to-oligodendrocyte propagation of α-synuclein in mouse and human models.
    Article Snippet: Briefly, Stempro hNSCs (Thermo Fisher Scientific, Waltham, MA, USA) were cultured in the OPC medium (CTS KnockOut DMEM/F12 with B-27 supplement minus vit.

    Article Title: Anti-TLR2 immunotherapy modulates neuron-to-oligodendrocyte propagation of α-synuclein in mouse and human models.
    Article Snippet: After differentiation to mature oligodendrocytes, 10 mg/ml of NM-101 or hIgG (HG4K, Sino Biological) was pre-treated for 30 minutes.

    Article Title: Anti-TLR2 immunotherapy modulates neuron-to-oligodendrocyte propagation of α-synuclein in mouse and human models
    Article Snippet: After cells were differentiated for 11 days, 10 mg/ml of NM-101 or hIgG (HG4K, Sino Biological, Beijing, China) was pre-treated for 30 min.

    Article Title: Anti-TLR2 immunotherapy modulates neuron-to-oligodendrocyte propagation of α-synuclein in mouse and human models
    Article Snippet: After differentiation to mature oligodendrocytes, 10 mg/ml of NM-101 or hIgG (HG4K, Sino Biological) was pre-treated for 30 min.



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    SNAP-AD 5 immunization elicited antigen-specific B cell response without high antigen-specific T cell response in mice. (A) Representative <t>ELISPOT</t> wells showing IFN-γ–secreting splenocytes from SNAP-AD 5 immunized, individual antigen immunized, or untreated control mice following stimulation with medium, individual antigens, or a 5-plex antigen mix. (B) Quantification of IFN-γ spots from (A) were counted and analyzed by a two-way ANOVA followed by Bonferroni's multiple comparison test, comparing each experimental group to the control, ∗p < 0.05. (C) Representative ELISPOT wells showed B-cell <t>producing</t> <t>IgG</t> in blood from mice (n = 5) immunized with SNAP-AD 5 or untreated mice. Blood cells after lysis were stimulated with medium alone, 10 μg/mL of Igκ/Igλ antibodies, or 10 μg/mL 5-plex mixed antigen. (D) Quantification of B-cell producing IgG spots from (C) were analyzed by a one-way ANOVA with multiple comparison followed by Tukey's test, ∗ P<0.05, ∗∗∗∗P<0.0001 .
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    Image Search Results


    SNAP-AD 5 immunization elicited antigen-specific B cell response without high antigen-specific T cell response in mice. (A) Representative ELISPOT wells showing IFN-γ–secreting splenocytes from SNAP-AD 5 immunized, individual antigen immunized, or untreated control mice following stimulation with medium, individual antigens, or a 5-plex antigen mix. (B) Quantification of IFN-γ spots from (A) were counted and analyzed by a two-way ANOVA followed by Bonferroni's multiple comparison test, comparing each experimental group to the control, ∗p < 0.05. (C) Representative ELISPOT wells showed B-cell producing IgG in blood from mice (n = 5) immunized with SNAP-AD 5 or untreated mice. Blood cells after lysis were stimulated with medium alone, 10 μg/mL of Igκ/Igλ antibodies, or 10 μg/mL 5-plex mixed antigen. (D) Quantification of B-cell producing IgG spots from (C) were analyzed by a one-way ANOVA with multiple comparison followed by Tukey's test, ∗ P<0.05, ∗∗∗∗P<0.0001 .

    Journal: Brain, Behavior, & Immunity - Health

    Article Title: Therapeutic nanoliposome vaccine targeting multiple Aβ and tau epitopes reduces AD-like brain pathologies and rescues cognitive deficits in 3xTg-AD mice

    doi: 10.1016/j.bbih.2025.101167

    Figure Lengend Snippet: SNAP-AD 5 immunization elicited antigen-specific B cell response without high antigen-specific T cell response in mice. (A) Representative ELISPOT wells showing IFN-γ–secreting splenocytes from SNAP-AD 5 immunized, individual antigen immunized, or untreated control mice following stimulation with medium, individual antigens, or a 5-plex antigen mix. (B) Quantification of IFN-γ spots from (A) were counted and analyzed by a two-way ANOVA followed by Bonferroni's multiple comparison test, comparing each experimental group to the control, ∗p < 0.05. (C) Representative ELISPOT wells showed B-cell producing IgG in blood from mice (n = 5) immunized with SNAP-AD 5 or untreated mice. Blood cells after lysis were stimulated with medium alone, 10 μg/mL of Igκ/Igλ antibodies, or 10 μg/mL 5-plex mixed antigen. (D) Quantification of B-cell producing IgG spots from (C) were analyzed by a one-way ANOVA with multiple comparison followed by Tukey's test, ∗ P<0.05, ∗∗∗∗P<0.0001 .

    Article Snippet: Mouse IFN-γ Single-Color ELISpot kit (ImmunoSpot, Cat# mIFNgp-2M/10) and Mouse IgG Single-Color ELISpot kit (ImmunoSpot, Cat# mIgG-SCE-2M/10) were purchased for ELISpot assays.

    Techniques: Enzyme-linked Immunospot, Control, Comparison, Lysis